rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
1
|
pubmed:dateCreated |
2007-8-24
|
pubmed:abstractText |
Myocardial gene and cellular therapies have revived the use of porcine ischemic heart models. Commonly applied ameroid-obstruction produces inconsistent coronary stenoses and myocardial lesions, whereas abrupt coronary occlusion causes arrhythmias and sudden death. To produce a constant myocardial lesion after adaptation to ischemia, we surgically modified the ameroid-model by ligation. As a pilot study for further cell therapy research, the spontaneous myocardial response is described.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0022-4804
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
142
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
195-201
|
pubmed:meshHeading |
pubmed-meshheading:17612566-Angiography,
pubmed-meshheading:17612566-Animals,
pubmed-meshheading:17612566-Caseins,
pubmed-meshheading:17612566-Coronary Disease,
pubmed-meshheading:17612566-Coronary Stenosis,
pubmed-meshheading:17612566-Disease Models, Animal,
pubmed-meshheading:17612566-Heart,
pubmed-meshheading:17612566-Hydrogels,
pubmed-meshheading:17612566-Ligation,
pubmed-meshheading:17612566-Myocardial Infarction,
pubmed-meshheading:17612566-Myocardial Ischemia,
pubmed-meshheading:17612566-Neovascularization, Physiologic,
pubmed-meshheading:17612566-Pilot Projects,
pubmed-meshheading:17612566-Regeneration,
pubmed-meshheading:17612566-Swine,
pubmed-meshheading:17612566-Tomography, Emission-Computed, Single-Photon
|
pubmed:year |
2007
|
pubmed:articleTitle |
Ligation of ameroid-stenosed coronary artery leads to reproducible myocardial infarction--a pilot study in a porcine model.
|
pubmed:affiliation |
Department of Vascular Surgery, University of Helsinki, Meilahti Hospital, Helsinki, Finland.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|