17603546

Source:http://linkedlifedata.com/resource/pubmed/id/17603546

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0014609, umls-concept:C0037659, umls-concept:C0205245, umls-concept:C0205419, umls-concept:C0302891, umls-concept:C0597357, umls-concept:C1707455
pubmed:issue	1
pubmed:dateCreated	2007-8-28
pubmed:abstractText	Somatostatin (SRIF-14) exerts broad spectrum antisecretory effects by activating the somatostatin 2 (sst(2)) receptor. The rat (r) sst(2) receptor exists in 'long' (sst(2a)) and 'short' (sst(2b)) forms that differ in their C termini, while a single human (h) sst(2a) exists. This study compares the characteristics of recombinant rsst(2a), rsst(2b) and hsst(2a) activation in human epithelia, and with native sst(2) responses in rat colon.
pubmed:commentsCorrections	http://linkedlifedata.com/resource/pubmed/commentcorrection/17603546-10398894, http://linkedlifedata.com/resource/pubmed/commentcorrection/17603546-10681540, http://linkedlifedata.com/resource/pubmed/commentcorrection/17603546-10818260, http://linkedlifedata.com/resource/pubmed/commentcorrection/17603546-11156595, http://linkedlifedata.com/resource/pubmed/commentcorrection/17603546-11585303, http://linkedlifedata.com/resource/pubmed/commentcorrection/17603546-12442323, http://linkedlifedata.com/resource/pubmed/commentcorrection/17603546-14694083, http://linkedlifedata.com/resource/pubmed/commentcorrection/17603546-15001578, http://linkedlifedata.com/resource/pubmed/commentcorrection/17603546-15361490, http://linkedlifedata.com/resource/pubmed/commentcorrection/17603546-15576634, http://linkedlifedata.com/resource/pubmed/commentcorrection/17603546-15855408, http://linkedlifedata.com/resource/pubmed/commentcorrection/17603546-16391492, http://linkedlifedata.com/resource/pubmed/commentcorrection/17603546-1679199, http://linkedlifedata.com/resource/pubmed/commentcorrection/17603546-16995043, http://linkedlifedata.com/resource/pubmed/commentcorrection/17603546-1706667, http://linkedlifedata.com/resource/pubmed/commentcorrection/17603546-2464148, http://linkedlifedata.com/resource/pubmed/commentcorrection/17603546-2906512, http://linkedlifedata.com/resource/pubmed/commentcorrection/17603546-3392683, http://linkedlifedata.com/resource/pubmed/commentcorrection/17603546-342100, http://linkedlifedata.com/resource/pubmed/commentcorrection/17603546-6156425, http://linkedlifedata.com/resource/pubmed/commentcorrection/17603546-7840190, http://linkedlifedata.com/resource/pubmed/commentcorrection/17603546-8104154, http://linkedlifedata.com/resource/pubmed/commentcorrection/17603546-8410493, http://linkedlifedata.com/resource/pubmed/commentcorrection/17603546-8532003, http://linkedlifedata.com/resource/pubmed/commentcorrection/17603546-8690197, http://linkedlifedata.com/resource/pubmed/commentcorrection/17603546-8762063, http://linkedlifedata.com/resource/pubmed/commentcorrection/17603546-9045884, http://linkedlifedata.com/resource/pubmed/commentcorrection/17603546-9630367, http://linkedlifedata.com/resource/pubmed/commentcorrection/17603546-9652348, http://linkedlifedata.com/resource/pubmed/commentcorrection/17603546-9695937, http://linkedlifedata.com/resource/pubmed/commentcorrection/17603546-9776362, http://linkedlifedata.com/resource/pubmed/commentcorrection/17603546-9886753
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/7502536
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/BIM 23027, http://linkedlifedata.com/resource/pubmed/chemical/BIM 23190, http://linkedlifedata.com/resource/pubmed/chemical/CYN 154806, http://linkedlifedata.com/resource/pubmed/chemical/Oligopeptides, http://linkedlifedata.com/resource/pubmed/chemical/Peptides, Cyclic, http://linkedlifedata.com/resource/pubmed/chemical/Piperazines, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Somatostatin, http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Somatostatin, http://linkedlifedata.com/resource/pubmed/chemical/Sstr2 protein, rat, http://linkedlifedata.com/resource/pubmed/chemical/somatostatin receptor sst2A
pubmed:status	MEDLINE
pubmed:month	Sep
pubmed:issn	0007-1188
pubmed:author	pubmed-author:CoxH MHM, pubmed-author:HollidayN DND, pubmed-author:ToughI RIR
pubmed:issnType	Print
pubmed:volume	152
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	132-40
pubmed:dateRevised	2009-11-18
pubmed:meshHeading	pubmed-meshheading:17603546-Animals, pubmed-meshheading:17603546-Cell Line, Tumor, pubmed-meshheading:17603546-Colon, pubmed-meshheading:17603546-Dose-Response Relationship, Drug, pubmed-meshheading:17603546-Epithelial Cells, pubmed-meshheading:17603546-Humans, pubmed-meshheading:17603546-Intestinal Mucosa, pubmed-meshheading:17603546-Male, pubmed-meshheading:17603546-Membrane Potentials, pubmed-meshheading:17603546-Oligopeptides, pubmed-meshheading:17603546-Peptides, Cyclic, pubmed-meshheading:17603546-Phosphorylation, pubmed-meshheading:17603546-Piperazines, pubmed-meshheading:17603546-Rats, pubmed-meshheading:17603546-Rats, Sprague-Dawley, pubmed-meshheading:17603546-Receptors, Somatostatin, pubmed-meshheading:17603546-Recombinant Proteins, pubmed-meshheading:17603546-Somatostatin, pubmed-meshheading:17603546-Time Factors, pubmed-meshheading:17603546-Transfection
pubmed:year	2007
pubmed:articleTitle	A functional comparison of recombinant and native somatostatin sst2 receptor variants in epithelia.
pubmed:affiliation	Wolfson Centre for Age-Related Diseases, King's College London, Hodgkin Building, Guy's Campus, London, UK.
pubmed:publicationType	Journal Article, Comparative Study, Research Support, Non-U.S. Gov't