Source:http://linkedlifedata.com/resource/pubmed/id/17599449
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
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| pubmed:dateCreated |
2007-6-29
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| pubmed:abstractText |
The purpose of this study was to report 1 center's experience with multidetector computed tomography (MDCT) in the evaluation of patients suspected to have arrhythmogenic right ventricular (RV) dysplasia/cardiomyopathy (ARVD/C). RV dilatation/dysfunction is 1 of the most important criteria for establishing the diagnosis of ARVD/C. Cardiac magnetic resonance imaging (MRI) is the most preferred imaging modality for the diagnosis of ARVD/C. However, many patients with suspected ARVD/C have implantable cardioverter-defibrillators, prohibiting the use of MRI. Thirty-one patients (19 men; mean age 41 +/- 12 years) referred for evaluation of known or suspected ARVD/C had a complete reevaluation including contrast-enhanced cardiac MDCT at the center. Two patients underwent both cardiac MRI and MDCT. Seventeen of 31 patients met Task Force criteria for ARVD/C and were confirmed to have ARVD/C. Multidetector computed tomographic images were analyzed for qualitative and quantitative characteristic findings of ARVD/C. Increased RV trabeculation (p <0.001), RV intramyocardial fat (p <0.001), and scalloping (p <0.001) were significantly associated with the final diagnosis of ARVD/C. RV volumes, RV inlet dimensions, and RV outflow tract surface area were increased in patients with ARVD/C compared with patients who did not meet the criteria. RV and left ventricular functional analysis was performed in 2 patients. In conclusion, cardiac MDCT has a strong potential to detect many qualitative and quantitative abnormalities of the right ventricle in patients with ARVD/C. Limitations include implantable cardioverter-defibrillators and motion artifacts, along with well-known radiation and contrast-induced reaction.
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| pubmed:grant | |
| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
AIM
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| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
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| pubmed:issn |
0002-9149
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| pubmed:author |
pubmed-author:BluemkeDavid ADA,
pubmed-author:BommaChandraC,
pubmed-author:CalkinsHughH,
pubmed-author:DalalDarshanD,
pubmed-author:DongJunJ,
pubmed-author:FishmanElliotE,
pubmed-author:JamesCynthiaC,
pubmed-author:LimaJoao A CJA,
pubmed-author:MaheshMahadevappaM,
pubmed-author:NasirKhurramK,
pubmed-author:PicciniJonathanJ,
pubmed-author:PrakasaKalpanaK,
pubmed-author:RoguinArielA,
pubmed-author:TandriHarikrishnaH,
pubmed-author:TichnellCrystalC
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| pubmed:issnType |
Print
|
| pubmed:day |
1
|
| pubmed:volume |
100
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
99-105
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| pubmed:dateRevised |
2007-12-3
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| pubmed:meshHeading |
pubmed-meshheading:17599449-Adult,
pubmed-meshheading:17599449-Arrhythmogenic Right Ventricular Dysplasia,
pubmed-meshheading:17599449-Female,
pubmed-meshheading:17599449-Heart Ventricles,
pubmed-meshheading:17599449-Humans,
pubmed-meshheading:17599449-Male,
pubmed-meshheading:17599449-Middle Aged,
pubmed-meshheading:17599449-Sensitivity and Specificity,
pubmed-meshheading:17599449-Tomography, X-Ray Computed
|
| pubmed:year |
2007
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| pubmed:articleTitle |
Evolving role of multidetector computed tomography in evaluation of arrhythmogenic right ventricular dysplasia/cardiomyopathy.
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| pubmed:affiliation |
Division of Cardiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
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| pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
|