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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3B
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pubmed:dateCreated |
2007-6-28
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pubmed:abstractText |
KIT functions as the receptor for stem cell factor (SCF) and this interaction is essential for regulation of proliferation and survival, particularly for germ cells since it regulates oogenesis, folliculogenesis and spermatogenesis. Up-regulation of KIT signalling has been associated with oncogenic transformation in cells expressing the molecule. Our objective was to investigate the expression of KIT in germ cell tumor patients and correlate it with the patients' clinical characteristics.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0250-7005
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pubmed:author |
pubmed-author:Arapantoni-DadiotiPP,
pubmed-author:AravantinosGG,
pubmed-author:EconomopoulosThT,
pubmed-author:FountzilasGG,
pubmed-author:GhicontiII,
pubmed-author:LekkaII,
pubmed-author:NikolaouMM,
pubmed-author:PectasidesDD,
pubmed-author:TamvakisNN,
pubmed-author:ValavanisCC,
pubmed-author:ZiziAA
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pubmed:issnType |
Print
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1685-8
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:17595797-Adolescent,
pubmed-meshheading:17595797-Adult,
pubmed-meshheading:17595797-Aged,
pubmed-meshheading:17595797-Drug Resistance, Neoplasm,
pubmed-meshheading:17595797-Humans,
pubmed-meshheading:17595797-Immunohistochemistry,
pubmed-meshheading:17595797-Male,
pubmed-meshheading:17595797-Middle Aged,
pubmed-meshheading:17595797-Neoplasms, Germ Cell and Embryonal,
pubmed-meshheading:17595797-Proto-Oncogene Proteins c-kit,
pubmed-meshheading:17595797-Up-Regulation
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pubmed:articleTitle |
Kit expression in male germ cell tumors.
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pubmed:affiliation |
Second Department of Internal Medicine-Propaedeutic, Attikon Hospital, Athens University Medical School, Greece. m_nikolaou@panafonet.gr
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pubmed:publicationType |
Journal Article
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