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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2007-8-7
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pubmed:abstractText |
Diabetes results in the upregulation of the production of several components of the inflammatory response in the retina, including inducible nitric oxide synthase (iNOS). The aim of this study was to investigate the role of iNOS in the pathogenesis of the early stages of diabetic retinopathy using iNOS-deficient mice (iNos (-/-)).
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0012-186X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1987-96
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pubmed:dateRevised |
2008-1-14
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pubmed:meshHeading |
pubmed-meshheading:17583794-Animals,
pubmed-meshheading:17583794-Capillaries,
pubmed-meshheading:17583794-Diabetes Mellitus, Experimental,
pubmed-meshheading:17583794-Diabetic Retinopathy,
pubmed-meshheading:17583794-Dinoprostone,
pubmed-meshheading:17583794-Mice,
pubmed-meshheading:17583794-Mice, Inbred C57BL,
pubmed-meshheading:17583794-Mice, Knockout,
pubmed-meshheading:17583794-Nitric Oxide,
pubmed-meshheading:17583794-Nitric Oxide Synthase Type II,
pubmed-meshheading:17583794-Reference Values,
pubmed-meshheading:17583794-Retina,
pubmed-meshheading:17583794-Retinal Degeneration,
pubmed-meshheading:17583794-Retinal Vessels,
pubmed-meshheading:17583794-Superoxides
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pubmed:year |
2007
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pubmed:articleTitle |
Critical role of inducible nitric oxide synthase in degeneration of retinal capillaries in mice with streptozotocin-induced diabetes.
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pubmed:affiliation |
Department of Medicine, 448B Biomedical Research Building, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106, USA. ling.zheng@case.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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