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pubmed-article:17580157pubmed:abstractTextThe minor histocompatibility antigen HA-1 occurs in two allelic forms: H and R. The HA-1(H) form presented in the context of HLA A2 can elicit specific cytotoxic lymphocyte (CTL) responses and can cause graft-versus-host disease in marrow transplants. However, its significance in solid organ transplants is unknown. We determined whether incompatibility of the HA-1 resulted in enhanced rejection and whether HA-1 specific CTLs were generated.lld:pubmed
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pubmed-article:17580157pubmed:articleTitleHA-1 mismatch has significant effect in chronic allograft nephropathy in clinical renal transplantation.lld:pubmed
pubmed-article:17580157pubmed:affiliationRenal Unit, University Hospitals Coventry and Warwickshire NHS Trust, Clifford Bridge Road, Coventry, England, UK. nithyaskrishnan@yahoo.co.uklld:pubmed
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