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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2007-6-20
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pubmed:abstractText |
The minor histocompatibility antigen HA-1 occurs in two allelic forms: H and R. The HA-1(H) form presented in the context of HLA A2 can elicit specific cytotoxic lymphocyte (CTL) responses and can cause graft-versus-host disease in marrow transplants. However, its significance in solid organ transplants is unknown. We determined whether incompatibility of the HA-1 resulted in enhanced rejection and whether HA-1 specific CTLs were generated.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0041-1345
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
39
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1439-45
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pubmed:meshHeading |
pubmed-meshheading:17580157-Adult,
pubmed-meshheading:17580157-Aged,
pubmed-meshheading:17580157-Chronic Disease,
pubmed-meshheading:17580157-Female,
pubmed-meshheading:17580157-Graft Rejection,
pubmed-meshheading:17580157-HLA-A2 Antigen,
pubmed-meshheading:17580157-Histocompatibility Testing,
pubmed-meshheading:17580157-Humans,
pubmed-meshheading:17580157-Kidney Transplantation,
pubmed-meshheading:17580157-Lymphocyte Culture Test, Mixed,
pubmed-meshheading:17580157-Male,
pubmed-meshheading:17580157-Middle Aged,
pubmed-meshheading:17580157-Minor Histocompatibility Antigens,
pubmed-meshheading:17580157-Oligopeptides,
pubmed-meshheading:17580157-Postoperative Complications,
pubmed-meshheading:17580157-Survival Analysis,
pubmed-meshheading:17580157-Transplantation Chimera
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pubmed:year |
2007
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pubmed:articleTitle |
HA-1 mismatch has significant effect in chronic allograft nephropathy in clinical renal transplantation.
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pubmed:affiliation |
Renal Unit, University Hospitals Coventry and Warwickshire NHS Trust, Clifford Bridge Road, Coventry, England, UK. nithyaskrishnan@yahoo.co.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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