Source:http://linkedlifedata.com/resource/pubmed/id/17577546
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2007-6-19
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pubmed:abstractText |
A rare case of anaplastic ameloblastic fibrosarcoma (AS) arising in an ameloblastic fibroma (AF) of the maxilla of a 48-year-old patient 10 years after the primary excision is presented. The recurrent tumor retained focal areas of AF but manifested heterogeneous malignant features ranging from low-grade spindle to highly pleomorphic sarcomas. Biomarker analysis showed alterations of the p53 and c-KIT genes restricted to the sarcomatous component. The biological implications of these findings in the future management of these tumors are discussed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
D
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1528-395X
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
104
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
72-5
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:17577546-Fibrosarcoma,
pubmed-meshheading:17577546-Genes, p53,
pubmed-meshheading:17577546-Humans,
pubmed-meshheading:17577546-Male,
pubmed-meshheading:17577546-Maxillary Neoplasms,
pubmed-meshheading:17577546-Middle Aged,
pubmed-meshheading:17577546-Neoplasm Recurrence, Local,
pubmed-meshheading:17577546-Neoplasms, Multiple Primary,
pubmed-meshheading:17577546-Odontoma,
pubmed-meshheading:17577546-Proto-Oncogene Proteins c-kit
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pubmed:year |
2007
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pubmed:articleTitle |
Anaplastic ameloblastic fibrosarcoma arising from recurrent ameloblastic fibroma: restricted molecular abnormalities of certain genes to the malignant transformation.
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pubmed:affiliation |
Department of Pathology, University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA. anaggar@mdanderson.org
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pubmed:publicationType |
Journal Article,
Case Reports
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