Linked Life Data

17560148

Source:http://linkedlifedata.com/resource/pubmed/id/17560148

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
2007-10-15
pubmed:abstractText
Synthesis of reactive oxygen species (ROS) by specific NADPH oxidases (Nox) can serve both defense and differentiation signaling roles in animals and plants. Fungi have three subfamilies of NADPH oxidase. NoxA and NoxB have a structure very similar to the human gp91(phox). NoxC has in addition a Ca(2+) binding motif as found in the human Nox5 and plant Rboh families of NADPH oxidases. A survey of fungal genomes identified up to four Nox genes in some fungal species, but Nox genes are absent from available genomes of the hemiascomycete yeasts, unicellular Basidiomycetes and Zygomycetes, reflecting the diversity of fungal life forms. Specific isoforms of Nox have been shown by genetic analysis to be required for various physiological processes and cellular differentiations, including development of sexual fruiting bodies, ascospore germination, hyphal defense, hyphal growth in both mutualistic and antagonistic plant-fungal interactions. This review provides an overview of our current knowledge of fungal NADPH oxidases, including Nox distribution in the fungal kingdom, Nox structure and regulation, and known biological functions of this important group of enzymes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1087-1845
pubmed:author
pubmed:issnType
Print
pubmed:volume
44
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1065-76
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
NADPH oxidases in fungi: diverse roles of reactive oxygen species in fungal cellular differentiation.
pubmed:affiliation
Centre for Functional Genomics, Institute of Molecular Biosciences, Massey University, Private Bag 11222, Palmerston North, New Zealand.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't