Linked Life Data

17546583

Source:http://linkedlifedata.com/resource/pubmed/id/17546583

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2007-7-9
pubmed:abstractText
In North America, the eastern spruce budworm, Choristoneura fumiferana Clem., is an important coniferous pest against which tebufenozide has proven effective as a control product. By acting as an ecdysone agonist, tebufenozide can induce precocious moulting in late (fifth-sixth) instars but can also be carried over to the next generation owing to its persistence on foliage. The authors conducted laboratory experiments on first-instar larvae treated with tebufenozide dissolved in acetone. Larvae exposed to doses equal to or above 0.1 microg cm(-2) displayed precocious moulting in the second instar after hibernaculum spinning, which effectively disrupted diapause. Larger doses induced moulting in first instars. Evidence is provided that this dose-response difference is related to whether or not an effective dose of tebufenozide is ingested by the first instar prior to the peak of moulting hormone (20-hydroxyecdysone) in first instars. Doses ineffective to kill first instars are carried over to the second instar, where they induce a precocious moult. This type of response to tebufenozide is dependent on the presence of a moulting machinery (the EcR-USP receptor complex) that is ready for ecdysone transduction. Interestingly, ecdysone levels are low in second instars, as measured by a radioimmunoassay, which suggests that diapause in spruce budworm is maintained by a suppression of ecdysone production. Thus, diapause disruption by tebufenozide may well provide an alternative control strategy for this important pest.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1526-498X
pubmed:author
pubmed:copyrightInfo
Copyright (c) 2007 Society of Chemical Industry
pubmed:issnType
Print
pubmed:volume
63
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
730-6
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Diapause disruption with tebufenozide for early-instar control of the spruce budworm, Choristoneura fumiferana.
pubmed:affiliation
Great Lakes Forestry Centre, Natural Resources Canada, Canadian Forest Service, Sault Ste. Marie, Ontario P6A 2E5, Canada. Dan.Doucet@nrcan.gc.ca
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't