Source:http://linkedlifedata.com/resource/pubmed/id/17521744
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2-3
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pubmed:dateCreated |
2007-8-13
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pubmed:abstractText |
Neurobiological mechanisms for social skills acquisition in schizophrenia remain largely unknown. We investigated whether an electrophysiological index of cognitive function predicts the degree of training-related social skills improvement in schizophrenia. Thirteen patients with schizophrenia underwent assessment of mismatch negativity (MMN) event-related potentials, followed by participation in a 3-month social skills training. Larger right frontal/temporal MMN current density values elicited by across-phoneme change were significantly associated with individual degrees of improvement in total social skills scores as assessed by a structured role play test. Although preliminary, these results suggest that phonetic MMN could be an index of social skills acquisition in patients with schizophrenia.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0165-1781
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
30
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pubmed:volume |
152
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
261-5
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pubmed:dateRevised |
2008-4-17
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pubmed:meshHeading |
pubmed-meshheading:17521744-Adult,
pubmed-meshheading:17521744-Cognition Disorders,
pubmed-meshheading:17521744-Electroencephalography,
pubmed-meshheading:17521744-Evoked Potentials,
pubmed-meshheading:17521744-Female,
pubmed-meshheading:17521744-Frontal Lobe,
pubmed-meshheading:17521744-Humans,
pubmed-meshheading:17521744-Learning,
pubmed-meshheading:17521744-Male,
pubmed-meshheading:17521744-Phonetics,
pubmed-meshheading:17521744-Questionnaires,
pubmed-meshheading:17521744-Schizophrenia,
pubmed-meshheading:17521744-Schizophrenic Psychology,
pubmed-meshheading:17521744-Social Behavior,
pubmed-meshheading:17521744-Social Perception,
pubmed-meshheading:17521744-Speech Perception,
pubmed-meshheading:17521744-Temporal Lobe
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pubmed:year |
2007
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pubmed:articleTitle |
Phonetic mismatch negativity predicts social skills acquisition in schizophrenia.
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pubmed:affiliation |
Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan. yukik-tky@umin.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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