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pubmed-article:17509887pubmed:abstractTextA series of stereoisomers for the azetidine ring of penaresidin B was synthesized and their cytotoxic and antimicrobial activities were evaluated. Among six synthetic isomers 1-6, isomers 4 and 5 showed relatively potent cytotoxic activity against A549 (lung) and HT29 (colon) tumor cells as well as antibacterial activity.lld:pubmed
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pubmed-article:17509887pubmed:articleTitleSynthesis of penaresidin derivatives and its biological activity.lld:pubmed
pubmed-article:17509887pubmed:affiliationGraduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.lld:pubmed
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