|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
14
|
|
pubmed:dateCreated |
2007-6-6
|
|
pubmed:abstractText |
A series of stereoisomers for the azetidine ring of penaresidin B was synthesized and their cytotoxic and antimicrobial activities were evaluated. Among six synthetic isomers 1-6, isomers 4 and 5 showed relatively potent cytotoxic activity against A549 (lung) and HT29 (colon) tumor cells as well as antibacterial activity.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jul
|
|
pubmed:issn |
0968-0896
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
15
|
|
pubmed:volume |
15
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
4910-6
|
|
pubmed:meshHeading |
pubmed-meshheading:17509887-Alkanes,
pubmed-meshheading:17509887-Anti-Bacterial Agents,
pubmed-meshheading:17509887-Cell Line, Tumor,
pubmed-meshheading:17509887-Cell Survival,
pubmed-meshheading:17509887-Heterocyclic Compounds, 1-Ring,
pubmed-meshheading:17509887-Humans,
pubmed-meshheading:17509887-Isomerism,
pubmed-meshheading:17509887-Molecular Structure,
pubmed-meshheading:17509887-Organic Chemicals,
pubmed-meshheading:17509887-Structure-Activity Relationship
|
|
pubmed:year |
2007
|
|
pubmed:articleTitle |
Synthesis of penaresidin derivatives and its biological activity.
|
|
pubmed:affiliation |
Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
