Linked Life Data

17485091

Source:http://linkedlifedata.com/resource/pubmed/id/17485091

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
13
pubmed:dateCreated
2007-5-25
pubmed:abstractText
AlphaI domain integrins have been found in the ascidian Ciona intestinalis. We produced Ciona alpha1I domain as a recombinant protein. It did not recognize fibril-forming collagens or bind to GFOGER or other similar motifs in triple-helical peptides. No GFOGER motifs were found in Ciona collagens. As Ciona alpha1I bound to collagen IX, we propose that before the emergence of GFOGER-dependent collagen receptors in vertebrates, alphaI domain integrins might have been able to bind to collagen with alternative mechanisms.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0014-5793
pubmed:author
pubmed:issnType
Print
pubmed:day
29
pubmed:volume
581
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2434-40
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Analysis of an ascidian integrin provides new insight into early evolution of collagen recognition.
pubmed:affiliation
Department of Biochemistry and Food Chemistry, University of Turku, Turku FI-20014, Finland. miratu@utu.fi
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't