Source:http://linkedlifedata.com/resource/pubmed/id/17477704
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2007-5-4
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pubmed:abstractText |
An 800-nm 200-fs laser is used to produce DNA damage in rat kangaroo (PtK1) and human cystic fibrosis pancreatic adenoma carcinoma (CFPAC-1) cells. Immunofluorescence staining for DNA repair factors in irradiated cells displays localization of gammaH2AX, Nbs1, and Rad50 to the site of irradiation 3 to 30 min following laser exposure. It is concluded that the 200-fs near-infrared laser is an excellent source for the production and study of spatially defined regions of DNA damage.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1083-3668
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
020505
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pubmed:dateRevised |
2007-12-3
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pubmed:meshHeading |
pubmed-meshheading:17477704-DNA,
pubmed-meshheading:17477704-DNA Damage,
pubmed-meshheading:17477704-DNA-Binding Proteins,
pubmed-meshheading:17477704-Dose-Response Relationship, Radiation,
pubmed-meshheading:17477704-Infrared Rays,
pubmed-meshheading:17477704-Lasers,
pubmed-meshheading:17477704-Radiation Dosage
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pubmed:articleTitle |
Recruitment of DNA damage recognition and repair pathway proteins following near-IR femtosecond laser irradiation of cells.
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pubmed:affiliation |
University of California-Irvine, Beckman Laser Institute, Irvine, California 92612, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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