Source:http://linkedlifedata.com/resource/pubmed/id/17461930
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2007-4-27
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pubmed:abstractText |
Hyperprothrombinemia, resulting from the prothrombin G20210A mutation or other causes, is associated with activated protein C (APC) resistance and increased thrombosis risk. When high prothrombin levels are a result of increased hepatic biosynthesis, these effects may be counteracted by concomitantly increased levels of the anticoagulant factors (particularly protein S). Differently, in prothrombin G20210A carriers only prothrombin levels are elevated.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1538-7933
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
971-9
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pubmed:meshHeading |
pubmed-meshheading:17461930-Adolescent,
pubmed-meshheading:17461930-Adult,
pubmed-meshheading:17461930-Aged,
pubmed-meshheading:17461930-Aged, 80 and over,
pubmed-meshheading:17461930-Base Sequence,
pubmed-meshheading:17461930-Child,
pubmed-meshheading:17461930-Child, Preschool,
pubmed-meshheading:17461930-DNA Primers,
pubmed-meshheading:17461930-Female,
pubmed-meshheading:17461930-Heterozygote Detection,
pubmed-meshheading:17461930-Humans,
pubmed-meshheading:17461930-Male,
pubmed-meshheading:17461930-Middle Aged,
pubmed-meshheading:17461930-Mutation,
pubmed-meshheading:17461930-Prothrombin,
pubmed-meshheading:17461930-Thrombin
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pubmed:year |
2007
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pubmed:articleTitle |
Differential effects of high prothrombin levels on thrombin generation depending on the cause of the hyperprothrombinemia.
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pubmed:affiliation |
Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands. e.castoldi@bioch.unimaas.nl
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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