Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2007-5-8
pubmed:abstractText
The aim of this study was to measure the accuracy of porosity of the mandibular cortex on dental panoramic radiographs (DPRs) in diagnosis of osteoporosis, alone and in combination with a clinical risk index. Six hundred seventy-one women (45-70yr) were recruited in the study, and dual-energy X-ray absorptiometry of the hip and lumbar spine was performed. A clinical index of osteoporosis risk (OSIRIS) and a DPR were obtained for each subject. The cortical appearance on the DPR was classified using the mandibular cortical index (MCI) by 5 observers. receiver operating characteristic (ROC) curve analysis was performed with calculation of area under the ROC curve (AUC) and sensitivity and specificity at various thresholds. Complete data were available for 653 subjects, of whom 21.6% had osteoporosis. The AUC for OSIRIS was 0.838. When used alone as the diagnostic test, MCI AUC for the 5 observers ranged from 0.560 to 0.670, significantly less than OSIRIS. Intraobserver and interobserver repeatability of MCI assessment was inconsistent. We conclude that MCI has limited value for osteoporosis diagnosis, being most appropriate as a method of fortuitous case-finding.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1094-6950
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
138-46
pubmed:meshHeading
pubmed-meshheading:17449308-Absorptiometry, Photon, pubmed-meshheading:17449308-Aged, pubmed-meshheading:17449308-Belgium, pubmed-meshheading:17449308-Bone Density, pubmed-meshheading:17449308-Diagnosis, Differential, pubmed-meshheading:17449308-Female, pubmed-meshheading:17449308-Great Britain, pubmed-meshheading:17449308-Greece, pubmed-meshheading:17449308-Humans, pubmed-meshheading:17449308-Incidence, pubmed-meshheading:17449308-Mandible, pubmed-meshheading:17449308-Middle Aged, pubmed-meshheading:17449308-Osteoporosis, Postmenopausal, pubmed-meshheading:17449308-ROC Curve, pubmed-meshheading:17449308-Radiography, Panoramic, pubmed-meshheading:17449308-Reproducibility of Results, pubmed-meshheading:17449308-Retrospective Studies, pubmed-meshheading:17449308-Risk Assessment, pubmed-meshheading:17449308-Risk Factors, pubmed-meshheading:17449308-Severity of Illness Index, pubmed-meshheading:17449308-Sweden
pubmed:articleTitle
The mandibular cortex on radiographs as a tool for osteoporosis risk assessment: the OSTEODENT Project.
pubmed:affiliation
School of Dentistry, University of Manchester, Manchester, UK. keith.horner@manchester.ac.uk
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't, Multicenter Study