Source:http://linkedlifedata.com/resource/pubmed/id/17441481
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2007-4-19
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pubmed:abstractText |
A 73-year-old male was admitted in January 1999 with hyperimmunoglobulinemia with a serum IgG level of 6530 mg/dl, bilateral eyelid tumors, bilateral submandibular swelling, and swelling of the superficial lymph nodes. A left submandibular gland biopsy showed severe chronic sialoadenitis with fibrosis. A left cervical lymph node biopsy showed invasion by many mature lymphocytes and plasma cells, but no lymphoma cells. The patient was diagnosed as having so-called Mikulicz disease associated with a disease similar to multicentric Castleman disease (MCD) characterized by multicentric lymphadenopathy and polyclonal hyperimmunoglobulinemia. Steroid therapy (prednisolone, 20 mg/day) was effective in reducing the symptoms, the bilateral eyelid tumors and the swelling of the bilateral submandibular glands and superficial lymph nodes. The lack of any increase of serum IL-6 suggested that this case had a hitherto unknown etiology, other than MCD.
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pubmed:language |
jpn
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0485-1439
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
229-34
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pubmed:meshHeading |
pubmed-meshheading:17441481-Aged,
pubmed-meshheading:17441481-Diagnosis, Differential,
pubmed-meshheading:17441481-Giant Lymph Node Hyperplasia,
pubmed-meshheading:17441481-Humans,
pubmed-meshheading:17441481-Hypergammaglobulinemia,
pubmed-meshheading:17441481-Immunoglobulin G,
pubmed-meshheading:17441481-Interleukin-6,
pubmed-meshheading:17441481-Lymphatic Diseases,
pubmed-meshheading:17441481-Male,
pubmed-meshheading:17441481-Mikulicz' Disease,
pubmed-meshheading:17441481-Prednisolone,
pubmed-meshheading:17441481-Treatment Outcome
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pubmed:year |
2007
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pubmed:articleTitle |
[Multicentric Castleman disease-like case characterized by lymphadenopathy and polyclonal hypergammaglobulinemia associated with so-called Mikulicz disease].
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pubmed:affiliation |
Department of Internal Medicine, Seichoukai Fuchu Hospital.
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pubmed:publicationType |
Journal Article,
English Abstract,
Case Reports
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