rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
7
|
pubmed:dateCreated |
2007-6-20
|
pubmed:abstractText |
This study investigates the impact of alpha-CGRP on bone metabolism after implantation of polyethylene particles. alpha-CGRP knockout mice showed less osteolysis compared with wildtype mice. The local neurogenic microenvironment might be a crucial factor in particle-induced osteolysis.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
0884-0431
|
pubmed:author |
pubmed-author:BylskiDavidD,
pubmed-author:GoshegerGeorgG,
pubmed-author:HeckeleiAnjaA,
pubmed-author:HilkenGeroG,
pubmed-author:LöerFranzF,
pubmed-author:NeuerburgCarlC,
pubmed-author:PfeifferAnneA,
pubmed-author:SaxlerGuidoG,
pubmed-author:SchinkeThorstenT,
pubmed-author:WedemeyerChristianC,
pubmed-author:von KnochFabianF,
pubmed-author:von KnochMariusM
|
pubmed:issnType |
Print
|
pubmed:volume |
22
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1011-9
|
pubmed:meshHeading |
pubmed-meshheading:17419680-Acid Phosphatase,
pubmed-meshheading:17419680-Animals,
pubmed-meshheading:17419680-Bone Resorption,
pubmed-meshheading:17419680-Calcitonin Gene-Related Peptide,
pubmed-meshheading:17419680-Cell Count,
pubmed-meshheading:17419680-Immunohistochemistry,
pubmed-meshheading:17419680-Implants, Experimental,
pubmed-meshheading:17419680-Isoenzymes,
pubmed-meshheading:17419680-Male,
pubmed-meshheading:17419680-Mice,
pubmed-meshheading:17419680-Mice, Inbred C57BL,
pubmed-meshheading:17419680-Mice, Knockout,
pubmed-meshheading:17419680-Osteoclasts,
pubmed-meshheading:17419680-Polyethylene,
pubmed-meshheading:17419680-RANK Ligand,
pubmed-meshheading:17419680-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:17419680-Skull,
pubmed-meshheading:17419680-Tomography, X-Ray Computed
|
pubmed:year |
2007
|
pubmed:articleTitle |
Polyethylene particle-induced bone resorption in alpha-calcitonin gene-related peptide-deficient mice.
|
pubmed:affiliation |
Department of Orthopaedics, University of Duisburg-Essen, Essen, Germany.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|