rdf:type |
|
lifeskim:mentions |
umls-concept:C0016055,
umls-concept:C0031437,
umls-concept:C0086418,
umls-concept:C0205360,
umls-concept:C0332256,
umls-concept:C0332281,
umls-concept:C0332461,
umls-concept:C0441889,
umls-concept:C1514562,
umls-concept:C1880389,
umls-concept:C1883204,
umls-concept:C1883221,
umls-concept:C2936350
|
pubmed:issue |
1
|
pubmed:dateCreated |
2007-10-19
|
pubmed:abstractText |
Extra domain A (EDA), splice-variant of fibronectin, is a Toll-like receptor 4 (Tlr4) ligand. Recently, EDA has been demonstrated to enhance atherogenesis in mice but human data on the role of EDA in atherosclerotic disease are lacking. We hypothesized that EDA is associated with unstable plaque phenotypes and that plasma EDA could serve as biomarker for atherosclerosis.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
1879-1484
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
195
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
e83-91
|
pubmed:dateRevised |
2007-12-27
|
pubmed:meshHeading |
pubmed-meshheading:17416372-Arteries,
pubmed-meshheading:17416372-Atherosclerosis,
pubmed-meshheading:17416372-Biological Markers,
pubmed-meshheading:17416372-Cohort Studies,
pubmed-meshheading:17416372-Fibronectins,
pubmed-meshheading:17416372-Gene Expression Regulation,
pubmed-meshheading:17416372-Humans,
pubmed-meshheading:17416372-Mammary Glands, Human,
pubmed-meshheading:17416372-Matrix Metalloproteinases,
pubmed-meshheading:17416372-Phenotype,
pubmed-meshheading:17416372-Prospective Studies,
pubmed-meshheading:17416372-Protein Structure, Tertiary,
pubmed-meshheading:17416372-Risk Factors,
pubmed-meshheading:17416372-Toll-Like Receptor 4
|
pubmed:year |
2007
|
pubmed:articleTitle |
Levels of extra domain A containing fibronectin in human atherosclerotic plaques are associated with a stable plaque phenotype.
|
pubmed:affiliation |
Experimental Cardiology Laboratory, Cardiology, University Medical Center Utrecht, The Netherlands.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|