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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2007-4-24
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pubmed:abstractText |
Previous reports indicate that compared with normoxia, 100% ventilatory O(2) during early reperfusion after global cerebral ischemia decreases hippocampal pyruvate dehydrogenase activity and increases neuronal death. However, current standards of care after cardiac arrest encourage the use of 100% O(2) during resuscitation and for an undefined period thereafter. Using a clinically relevant canine cardiac arrest model, in this study we tested the hypothesis that hyperoxic reperfusion decreases hippocampal glucose metabolism and glutamate synthesis.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/17413048-10217272,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17413048-10683278,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17413048-11181817,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17413048-11740207,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17413048-11926275,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17413048-12677019,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17413048-12796718,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17413048-14679504,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17413048-1519288,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17413048-15593283,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17413048-16251887,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17413048-16504342,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17413048-16716897,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17413048-1968068,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17413048-2715207,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17413048-3614648,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17413048-3884090,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17413048-7103425,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17413048-8070685,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17413048-8086011,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17413048-9422367,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17413048-9593822,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17413048-9596256,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17413048-9667336,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17413048-9707212
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1524-4628
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1578-84
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:17413048-Animals,
pubmed-meshheading:17413048-Brain Ischemia,
pubmed-meshheading:17413048-Cardiopulmonary Resuscitation,
pubmed-meshheading:17413048-Dogs,
pubmed-meshheading:17413048-Energy Metabolism,
pubmed-meshheading:17413048-Female,
pubmed-meshheading:17413048-Glucose,
pubmed-meshheading:17413048-Glutamic Acid,
pubmed-meshheading:17413048-Heart Arrest,
pubmed-meshheading:17413048-Hippocampus,
pubmed-meshheading:17413048-Oxidative Stress,
pubmed-meshheading:17413048-Oxygen Inhalation Therapy,
pubmed-meshheading:17413048-Reperfusion Injury,
pubmed-meshheading:17413048-Respiration, Artificial
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pubmed:year |
2007
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pubmed:articleTitle |
Hyperoxic reperfusion after global ischemia decreases hippocampal energy metabolism.
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pubmed:affiliation |
Program in Neuroscience, the Department of Anesthesiology, University of Maryland School of Medicine, Baltimore, MD, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, N.I.H., Extramural
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