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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2007-4-30
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pubmed:abstractText |
The Gln allele of the Arg462Gln polymorphism in RNASEL results in a threefold decrease in enzymatic activity, a reported deficiency in apoptotic response, and has been associated with prostate cancer in some high-risk family studies. The relationship of this variant to sporadic prostate cancer remains uncertain.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0270-4137
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2007 Wiley-Liss, Inc.
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
67
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
849-54
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pubmed:dateRevised |
2011-6-17
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pubmed:meshHeading |
pubmed-meshheading:17407163-Adenocarcinoma,
pubmed-meshheading:17407163-Aged,
pubmed-meshheading:17407163-Anti-Inflammatory Agents, Non-Steroidal,
pubmed-meshheading:17407163-Case-Control Studies,
pubmed-meshheading:17407163-DNA,
pubmed-meshheading:17407163-Endoribonucleases,
pubmed-meshheading:17407163-Genotype,
pubmed-meshheading:17407163-Humans,
pubmed-meshheading:17407163-Male,
pubmed-meshheading:17407163-Mass Screening,
pubmed-meshheading:17407163-Middle Aged,
pubmed-meshheading:17407163-Polymorphism, Genetic,
pubmed-meshheading:17407163-Prostatic Neoplasms,
pubmed-meshheading:17407163-Sequence Analysis, DNA
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pubmed:year |
2007
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pubmed:articleTitle |
RNASEL Arg462Gln polymorphism and prostate cancer in PLCO.
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pubmed:affiliation |
Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA. daughers@mail.nih.gov
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural,
Research Support, N.I.H., Intramural
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