rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2007-5-30
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pubmed:abstractText |
We previously reported that increase in plasma homocysteine (Hcys) levels by a 6-week methionine treatment produced remarkable glomerular injury. However, the mechanism by which hyperhomocysteinemia (hHcys) produces glomerular injury remains unknown. The present study was to observe when glomerular injury happens during hHcys and to explore the possible role of podocyte injury in the progression of glomerulosclerosis associated with hHcys.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Actinin,
http://linkedlifedata.com/resource/pubmed/chemical/Actn4 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Creatinine,
http://linkedlifedata.com/resource/pubmed/chemical/Homocysteine,
http://linkedlifedata.com/resource/pubmed/chemical/Intracellular Signaling Peptides...,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Methionine,
http://linkedlifedata.com/resource/pubmed/chemical/Microfilament Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/NPHS2 protein,
http://linkedlifedata.com/resource/pubmed/chemical/nephrin
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pubmed:status |
MEDLINE
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pubmed:issn |
1421-9670
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pubmed:author |
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pubmed:copyrightInfo |
2007 S. Karger AG, Basel
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pubmed:issnType |
Electronic
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
262-8
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pubmed:dateRevised |
2007-12-3
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pubmed:meshHeading |
pubmed-meshheading:17396029-Actinin,
pubmed-meshheading:17396029-Albuminuria,
pubmed-meshheading:17396029-Animals,
pubmed-meshheading:17396029-Creatinine,
pubmed-meshheading:17396029-Glomerulosclerosis, Focal Segmental,
pubmed-meshheading:17396029-Homocysteine,
pubmed-meshheading:17396029-Hyperhomocysteinemia,
pubmed-meshheading:17396029-Intracellular Signaling Peptides and Proteins,
pubmed-meshheading:17396029-Membrane Proteins,
pubmed-meshheading:17396029-Methionine,
pubmed-meshheading:17396029-Microfilament Proteins,
pubmed-meshheading:17396029-Podocytes,
pubmed-meshheading:17396029-Rats,
pubmed-meshheading:17396029-Rats, Sprague-Dawley,
pubmed-meshheading:17396029-Time Factors
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pubmed:year |
2007
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pubmed:articleTitle |
Podocyte injury and glomerulosclerosis in hyperhomocysteinemic rats.
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pubmed:affiliation |
Department of Pharmacology and Toxicology, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA 23298, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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