|
pubmed:abstractText |
To develop a method of direct intravesical administration of acrolein and evaluate the severity of cystitis in response to increasing doses of acrolein in female C57BL/6N (C57) mice, with further studies to compare the severity of acute acrolein-induced cystitis among C57, C3H/HeJ (HeJ), and C3H/OuJ (OuJ) strains of mice, as chemical cystitis produced by the systemic administration of cyclophosphamide is thought to result from renal excretion of hepatic metabolites, particularly acrolein.
|
|
pubmed:affiliation |
Department of Surgical Sciences, School of Veterinary, University of Wisconsin, Madison, WI 53706, USA. bjorlind@svm.vetmed.wisc.edu
|
