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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2007-3-9
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pubmed:abstractText |
Highly active antiretroviral therapy (HAART) can successfully reduce plasma and tissue levels of HIV-1 RNA and results in reductions in HIV-related morbidity and mortality, but the slow viral evolution during therapy in cellular reservoirs is a continuing problem. In addition, little remains known how viral evolutionary process may differ between cell-free and cell-associated compartments, over time, in vivo in patients receiving HAART or STI.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1873-4251
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
235-50
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:17346137-Adult,
pubmed-meshheading:17346137-Antiretroviral Therapy, Highly Active,
pubmed-meshheading:17346137-Cell Culture Techniques,
pubmed-meshheading:17346137-Drug Administration Schedule,
pubmed-meshheading:17346137-Drug Resistance, Viral,
pubmed-meshheading:17346137-Evolution, Molecular,
pubmed-meshheading:17346137-Gene Products, env,
pubmed-meshheading:17346137-Genes, env,
pubmed-meshheading:17346137-HIV Protease,
pubmed-meshheading:17346137-HIV Reverse Transcriptase,
pubmed-meshheading:17346137-HIV-1,
pubmed-meshheading:17346137-Humans,
pubmed-meshheading:17346137-Leukocytes, Mononuclear,
pubmed-meshheading:17346137-Male,
pubmed-meshheading:17346137-Middle Aged,
pubmed-meshheading:17346137-Molecular Sequence Data,
pubmed-meshheading:17346137-Phylogeny,
pubmed-meshheading:17346137-Plasma,
pubmed-meshheading:17346137-Sequence Analysis, Protein,
pubmed-meshheading:17346137-Viral Load,
pubmed-meshheading:17346137-Virus Replication
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pubmed:year |
2007
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pubmed:articleTitle |
Drug resistance and viral evolution in plasma and peripheral blood cells during structured treatment interruption (STI) and non-interrupted HAART.
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pubmed:affiliation |
Retroviral Genetics Laboratory, Centre for Virus Research, Westmead Millennium Institutes, Westmead Hospital, The University of Sydney, Sydney, Australia.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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