Linked Life Data

17344529

Source:http://linkedlifedata.com/resource/pubmed/id/17344529

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2007-10-18
pubmed:abstractText
Although the epidemiology of coccidioidomycosis has been well described, there is a paucity of recent data on the public health burden associated with this disease. Accordingly, California's Inpatient Hospital Discharge Data Set from 1997 to 2002 was used to calculate the incidence of hospitalization for coccidioidomycosis by county, year, age, race, ethnicity, and gender. The overall finding that coccidioidomycosis has a significant impact in endemic areas supports the conclusion that the need for a preventive vaccine is great. Investigators of the Valley Fever Vaccine Project (VFVP) have successfully identified a number of recombinant coccidioidal protein antigens and two attenuated mutant strains that have been evaluated as vaccines, demonstrating protective responses in murine models. Efforts to select and develop a vaccine for human clinical trials are in progress.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0077-8923
pubmed:author
pubmed:issnType
Print
pubmed:volume
1111
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
259-68
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
The public health need and present status of a vaccine for the prevention of coccidioidomycosis.
pubmed:affiliation
Institute for Global Health, University of California, San Francisco, 50 Beale St., Suite 1200, San Francisco, CA 94105, USA. rhector@psg.ucsf.edu
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't