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pubmed-article:17344026pubmed:abstractTextThe methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism has been associated with both overall schizophrenia risk and severity of negative symptoms. This study examined whether schizophrenia patients homozygous for the risk allele (T/T) exhibit greater impairment in executive function, and determined the extent to which MTHFR's effects on negative symptoms underlie this relationship.lld:pubmed
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pubmed-article:17344026pubmed:articleTitleEffects of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism on executive function in schizophrenia.lld:pubmed
pubmed-article:17344026pubmed:affiliationSchizophrenia Research Program, Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, USA. jroffman@partners.orglld:pubmed
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