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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2007-5-4
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pubmed:abstractText |
Celiac disease is an enteropathy featuring villous atrophy, crypt hyperplasia, and lymphocytosis. Tissue remodeling is driven by an inflammatory reaction to gluten in genetically susceptible individuals. The adaptive pathway is considered the major immune response but recent evidence has indicated the involvement of innate immunity as well. To assess the contribution of either immune response we performed global gene expression profiling of the regenerating mucosa.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1542-7714
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
574-81
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pubmed:meshHeading |
pubmed-meshheading:17336591-Adolescent,
pubmed-meshheading:17336591-Adult,
pubmed-meshheading:17336591-Aged,
pubmed-meshheading:17336591-Aged, 80 and over,
pubmed-meshheading:17336591-Case-Control Studies,
pubmed-meshheading:17336591-Celiac Disease,
pubmed-meshheading:17336591-Child,
pubmed-meshheading:17336591-Child, Preschool,
pubmed-meshheading:17336591-Female,
pubmed-meshheading:17336591-Gene Expression Profiling,
pubmed-meshheading:17336591-Humans,
pubmed-meshheading:17336591-Infant,
pubmed-meshheading:17336591-Intestinal Absorption,
pubmed-meshheading:17336591-Lymphocyte Activation,
pubmed-meshheading:17336591-Male,
pubmed-meshheading:17336591-Middle Aged,
pubmed-meshheading:17336591-Neutrophil Infiltration,
pubmed-meshheading:17336591-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:17336591-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:17336591-Th1 Cells
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pubmed:year |
2007
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pubmed:articleTitle |
Neutrophil recruitment and barrier impairment in celiac disease: a genomic study.
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pubmed:affiliation |
Department of Medical Genetics, Division of Biomedical Genetics, University Medical Center, Utrecht, The Netherlands.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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