rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1 Suppl
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pubmed:dateCreated |
2007-3-2
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pubmed:abstractText |
The currently available biological markers are limited in sensitivity and specificity for screening of excessive alcohol drinkers. We recently purified and identified 3 potential markers for alcoholism (5.9 and 7.8 kDa peptides and 28 kDa protein) by using surface-enhanced laser desorption/ionization (SELDI-TOF MS) technology. In the present study, we determined the diagnostic values of these novel markers in screening habitual drinkers with moderate alcohol consumption (hereafter habitual drinkers) in the general population as compared with 2 conventional markers: gamma-glutamyltransferase (GGT) and carbohydrate-deficient transferrin (CDT).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1530-0277
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
S22-6
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:17331162-Adult,
pubmed-meshheading:17331162-Aged,
pubmed-meshheading:17331162-Alcoholism,
pubmed-meshheading:17331162-Apolipoproteins A,
pubmed-meshheading:17331162-Biological Markers,
pubmed-meshheading:17331162-Fibrin Fibrinogen Degradation Products,
pubmed-meshheading:17331162-Humans,
pubmed-meshheading:17331162-Japan,
pubmed-meshheading:17331162-Male,
pubmed-meshheading:17331162-Mass Screening,
pubmed-meshheading:17331162-Middle Aged,
pubmed-meshheading:17331162-Predictive Value of Tests,
pubmed-meshheading:17331162-Proteomics,
pubmed-meshheading:17331162-Spectrometry, Mass, Matrix-Assisted Laser...,
pubmed-meshheading:17331162-Transferrin,
pubmed-meshheading:17331162-gamma-Glutamyltransferase
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pubmed:year |
2007
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pubmed:articleTitle |
Diagnostic values of surface-enhanced laser desorption/ionization technology for screening of habitual drinkers.
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pubmed:affiliation |
Department of Molecular Diagnosis, Graduate School of Medicine, Chiba University, Chiba, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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