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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2007-3-23
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pubmed:abstractText |
Tissue factor (TF), the initiator of coagulation, circulates in blood and contributes to thrombosis in patients with coronary artery disease (CAD). TF is present in the alpha-granules of platelets. Therapy with clopidogrel results in inhibition of platelet degranulation. Whether clopidogrel affects circulating TF is unknown. This study examined the effect of clopidogrel on TF level in the blood of patients with stable CAD and ST-elevation myocardial infarction (STEMI) as well as healthy controls.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0902-4441
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
78
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
347-52
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:17331131-Adult,
pubmed-meshheading:17331131-CD40 Ligand,
pubmed-meshheading:17331131-Coronary Artery Disease,
pubmed-meshheading:17331131-Female,
pubmed-meshheading:17331131-Humans,
pubmed-meshheading:17331131-Male,
pubmed-meshheading:17331131-Middle Aged,
pubmed-meshheading:17331131-Myocardial Infarction,
pubmed-meshheading:17331131-Platelet Aggregation Inhibitors,
pubmed-meshheading:17331131-Solubility,
pubmed-meshheading:17331131-Thromboplastin,
pubmed-meshheading:17331131-Ticlopidine,
pubmed-meshheading:17331131-Treatment Outcome
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pubmed:year |
2007
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pubmed:articleTitle |
Clopidogrel-mediated reduction of circulating tissue factor in patients with stable coronary artery disease.
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pubmed:affiliation |
Department of Cardiology and Pneumology, Charité-Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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