Linked Life Data

17313591

Source:http://linkedlifedata.com/resource/pubmed/id/17313591

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2007-2-22
pubmed:abstractText
Helicobacter pylori is a Gram-negative microaerophilic organism that colonizes the gastric mucosa of humans. Helicobacter pylori is one of the most common infections in humans and results in the development of gastritis in all infected individuals, although the majority of people are asymptomatic. A subset of infected people develop serious disease including duodenal ulceration and gastric cancer. Helicobacter pylori exhibits many striking characteristics. It lives in the hostile environment of the stomach and displays a very strict host and tissue tropism. Despite a vigorous immune response, infection persists for the lifetime of the host unless eradicated with antimicrobials. Why H. pylori is so pathogenic in some individuals and not in others is unknown but is thought to be due to a variety of host, environmental and bacterial factors. In this review, some of the bacterial factors that mediate colonization of the gastric mucosa and play a role in the pathogenesis of this organism have been considered.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0378-1097
pubmed:author
pubmed:issnType
Print
pubmed:volume
268
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
135-43
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Bacterial factors that mediate colonization of the stomach and virulence of Helicobacter pylori.
pubmed:affiliation
UCD School of Medicine and Medical Science, The Children's Research Ctr, Our Lady's Children's Hospital Crumlin, Dublin, Ireland. marguerite.clyne@ucd.ie
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't