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rdf:type |
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|
lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2007-2-8
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pubmed:abstractText |
The inability of radiotherapy to eradicate completely certain human tumours may be due to the presence of resistant hypoxic cells. Several studies have confirmed the radiosensitizing effect of paclitaxel, a microtubular inhibitor. The object of this study was to evaluate the physicochemical characteristics of paclitaxel-loaded nanoparticles, and determine the ability of the released paclitaxel to radiosensitize hypoxic human breast carcinoma cells (MCF-7) with respect to radiation dose.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0269-4727
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
32
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
41-7
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pubmed:dateRevised |
2008-5-28
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pubmed:meshHeading |
pubmed-meshheading:17286788-Antineoplastic Agents, Phytogenic,
pubmed-meshheading:17286788-Breast Neoplasms,
pubmed-meshheading:17286788-Cell Line, Tumor,
pubmed-meshheading:17286788-Combined Modality Therapy,
pubmed-meshheading:17286788-Delayed-Action Preparations,
pubmed-meshheading:17286788-Drug Carriers,
pubmed-meshheading:17286788-Humans,
pubmed-meshheading:17286788-Lactic Acid,
pubmed-meshheading:17286788-Nanoparticles,
pubmed-meshheading:17286788-Paclitaxel,
pubmed-meshheading:17286788-Particle Size,
pubmed-meshheading:17286788-Polyglycolic Acid,
pubmed-meshheading:17286788-Polymers
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|
pubmed:year |
2007
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|
pubmed:articleTitle |
The effect of paclitaxel-loaded nanoparticles with radiation on hypoxic MCF-7 cells.
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pubmed:affiliation |
Department of Radiation Medicine, Fourth Military Medical University, Xi'an, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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