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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2007-5-30
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pubmed:abstractText |
NOD1/CARD4 and NOD2/CARD15 are both intracellular pattern-recognition receptors. The NOD1/CARD4 gene lies within a previously described inflammatory bowel disease (IBD) locus (7p14). An association has been suggested between the NOD1/CARD4+32656 deletion*1 variant of a complex deletion*1/insertion*2 polymorphism and IBD in 1 recent study in Europe. Our aim was to assess the influence of NOD1/CARD4+32656 on disease susceptibility and phenotype in the Scottish and Swedish IBD populations.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1078-0998
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pubmed:author |
pubmed-author:AndersonN HNH,
pubmed-author:ArnottI DID,
pubmed-author:BissetW MWM,
pubmed-author:DrummondH EHE,
pubmed-author:DunlopM GMG,
pubmed-author:FarringtonS MSM,
pubmed-author:GillettP MPM,
pubmed-author:HassanKK,
pubmed-author:LördalMM,
pubmed-author:LeesC WCW,
pubmed-author:MahdiGG,
pubmed-author:McGroganPP,
pubmed-author:NimmoE RER,
pubmed-author:RussellR KRK,
pubmed-author:SatsangiJJ,
pubmed-author:SjöqvistUU,
pubmed-author:SmithLL,
pubmed-author:TörkvistLL,
pubmed-author:Van LimbergenJJ,
pubmed-author:WeaverL TLT,
pubmed-author:WilsonD CDC
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pubmed:issnType |
Print
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
882-9
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pubmed:dateRevised |
2008-5-7
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pubmed:meshHeading |
pubmed-meshheading:17285593-Adolescent,
pubmed-meshheading:17285593-Adult,
pubmed-meshheading:17285593-Age of Onset,
pubmed-meshheading:17285593-Case-Control Studies,
pubmed-meshheading:17285593-Child,
pubmed-meshheading:17285593-Female,
pubmed-meshheading:17285593-Genetic Predisposition to Disease,
pubmed-meshheading:17285593-Genotype,
pubmed-meshheading:17285593-Humans,
pubmed-meshheading:17285593-Inflammatory Bowel Diseases,
pubmed-meshheading:17285593-Male,
pubmed-meshheading:17285593-Middle Aged,
pubmed-meshheading:17285593-Mutation,
pubmed-meshheading:17285593-Nod1 Signaling Adaptor Protein,
pubmed-meshheading:17285593-Phenotype,
pubmed-meshheading:17285593-Polymorphism, Genetic,
pubmed-meshheading:17285593-Scotland,
pubmed-meshheading:17285593-Sweden
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pubmed:year |
2007
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pubmed:articleTitle |
Contribution of the NOD1/CARD4 insertion/deletion polymorphism +32656 to inflammatory bowel disease in Northern Europe.
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pubmed:affiliation |
Gastrointestinal Unit, Molecular Medicine Centre, Western General Hospital, University of Edinburgh, Edinburgh, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Multicenter Study
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