Linked Life Data

17271063

Source:http://linkedlifedata.com/resource/pubmed/id/17271063

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2007-2-2
pubmed:abstractText
The increasing availability of murine models of the cardiovascular system has created a need for instrumentation and methods for assessing murine cardiovascular function. We have adapted an existing optical mapping system based on voltage-sensitive dyes to record from an isolated mouse atrial preparation. Initial results indicate that our approach is capable of recording action potentials from isolated mouse atria with sufficient signal quality to determine action potential duration (APD). Preliminary observations suggest that gradients in APD exist in the mouse atria and are similar to those observed in the atria of larger mammals. Future work with this technique will provide important information about mouse atrial electrophysiology and how it relates to that of larger mammals.
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:issn
1557-170X
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3576-7
pubmed:year
2004
pubmed:articleTitle
Optical mapping system for recording action potential durations in adult mouse left and right atrium.
pubmed:affiliation
Department of Physiology & Biophysics, University of Calgary, Canada.
pubmed:publicationType
Journal Article