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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2007-3-5
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pubmed:abstractText |
Olanzapine is a neuroleptic drug widely prescribed to treat schizophrenia and bipolar disorder. Although it is long known that modulation of the dopamine system is a basic mechanism of action of neuroleptics, their impact on reward functions mediated by dopamine is still poorly understood.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0033-3158
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
191
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
823-33
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:17265148-Antipsychotic Agents,
pubmed-meshheading:17265148-Basal Ganglia,
pubmed-meshheading:17265148-Benzodiazepines,
pubmed-meshheading:17265148-Brain,
pubmed-meshheading:17265148-Cerebrovascular Circulation,
pubmed-meshheading:17265148-Cross-Over Studies,
pubmed-meshheading:17265148-Dopamine,
pubmed-meshheading:17265148-Double-Blind Method,
pubmed-meshheading:17265148-Humans,
pubmed-meshheading:17265148-Hypercapnia,
pubmed-meshheading:17265148-Magnetic Resonance Imaging,
pubmed-meshheading:17265148-Motivation,
pubmed-meshheading:17265148-Oxygen,
pubmed-meshheading:17265148-Oxygen Consumption,
pubmed-meshheading:17265148-Pilot Projects,
pubmed-meshheading:17265148-Prefrontal Cortex,
pubmed-meshheading:17265148-Reaction Time,
pubmed-meshheading:17265148-Reference Values,
pubmed-meshheading:17265148-Reward,
pubmed-meshheading:17265148-Serotonin Uptake Inhibitors
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pubmed:year |
2007
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pubmed:articleTitle |
Human reward system activation is modulated by a single dose of olanzapine in healthy subjects in an event-related, double-blind, placebo-controlled fMRI study.
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pubmed:affiliation |
Department of Psychiatry, University of Ulm, Leimgrubenweg 12-14, 89075, Ulm, Germany. birgit.abler@uni-ulm.de
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial
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