17265078

Source:http://linkedlifedata.com/resource/pubmed/id/17265078

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0035397, umls-concept:C0068897, umls-concept:C0086418, umls-concept:C0599946, umls-concept:C1879547
pubmed:issue	4
pubmed:dateCreated	2007-3-9
pubmed:abstractText	The rewarding effects of ethanol and other drugs of abuse are mediated by activation of the mesolimbic dopamine system. Recent neuroimaging studies in primates and humans suggest that cocaine-induced dopamine stimulation might be diminished by drugs augmenting gamma-aminobutyric acid A (GABA-A) receptor function such as the GABA transaminase inhibitor vigabatrin.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/7608025
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Central Nervous System Depressants, http://linkedlifedata.com/resource/pubmed/chemical/Ethanol, http://linkedlifedata.com/resource/pubmed/chemical/Fluorodeoxyglucose F18, http://linkedlifedata.com/resource/pubmed/chemical/GABA Plasma Membrane Transport..., http://linkedlifedata.com/resource/pubmed/chemical/GABA Uptake Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Neurotransmitter Uptake Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Nipecotic Acids, http://linkedlifedata.com/resource/pubmed/chemical/Radiopharmaceuticals, http://linkedlifedata.com/resource/pubmed/chemical/SLC6A1 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/gamma-Aminobutyric Acid, http://linkedlifedata.com/resource/pubmed/chemical/tiagabine
pubmed:status	MEDLINE
pubmed:month	May
pubmed:issn	0033-3158
pubmed:author	pubmed-author:BartensteinPeterP, pubmed-author:BuchholzHans-GeorgHG, pubmed-author:ChechkoNatalieN, pubmed-author:DielentheisThomas FTF, pubmed-author:FehrChristophC, pubmed-author:GründerGerhardG, pubmed-author:HohmannNinaN, pubmed-author:LandvogtChristianC, pubmed-author:SchreckenbergerMathiasM, pubmed-author:UrbanReinhardR, pubmed-author:YakushevIgorI
pubmed:issnType	Print
pubmed:volume	191
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	975-83
pubmed:dateRevised	2010-11-18
pubmed:meshHeading	pubmed-meshheading:17265078-Adult, pubmed-meshheading:17265078-Behavior, Addictive, pubmed-meshheading:17265078-Central Nervous System Depressants, pubmed-meshheading:17265078-Drug Synergism, pubmed-meshheading:17265078-Ethanol, pubmed-meshheading:17265078-Fluorodeoxyglucose F18, pubmed-meshheading:17265078-GABA Plasma Membrane Transport Proteins, pubmed-meshheading:17265078-GABA Uptake Inhibitors, pubmed-meshheading:17265078-Humans, pubmed-meshheading:17265078-Limbic System, pubmed-meshheading:17265078-Male, pubmed-meshheading:17265078-Neurotransmitter Uptake Inhibitors, pubmed-meshheading:17265078-Nipecotic Acids, pubmed-meshheading:17265078-Positron-Emission Tomography, pubmed-meshheading:17265078-Radiopharmaceuticals, pubmed-meshheading:17265078-Reference Values, pubmed-meshheading:17265078-Reward, pubmed-meshheading:17265078-Single-Blind Method, pubmed-meshheading:17265078-gamma-Aminobutyric Acid
pubmed:year	2007
pubmed:articleTitle	Tiagabine does not attenuate alcohol-induced activation of the human reward system.
pubmed:affiliation	Department of Psychiatry, University of Mainz, Untere Zahlbacher Strasse 8, 55131, Mainz, Germany. fehrc@uni-mainz.de
pubmed:publicationType	Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't