Linked Life Data

1725837

Source:http://linkedlifedata.com/resource/pubmed/id/1725837

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1992-6-3
pubmed:abstractText
Previous studies have shown that oral immunization with Salmonella typhi Ty21a-based clones expressing Vibrio cholerae O-antigen elicits serum antibody responses against the foreign polysaccharide in human volunteers. These responses are conveniently assayed by complement-dependent bacteriolysis of V. cholerae. In this report the bactericidal responses generated by two such clones are analysed in relation to the pre-immunization titres of various serum antibodies. A significant association was found, in that recipients with higher prevaccine titres of anti-V. cholerae bactericidal antibodies were less likely to register significant bactericidal responses following immunization. These results are discussed in relation to the concept of vaccine exclusion.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0264-410X
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
877-82
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Oral immunization with Salmonella typhi Ty21a-based clones expressing Vibrio cholerae O-antigen: serum bactericidal antibody responses in man in relation to pre-immunization antibody levels.
pubmed:affiliation
Department of Microbiology & Immunology, University of Adelaide, South Australia.
pubmed:publicationType
Journal Article