rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
6B
|
pubmed:dateCreated |
2007-1-4
|
pubmed:abstractText |
A C-->A polymorphism within the CDH1 (E-cadherin) promoter seems to be associated with a reduced efficiency of gene transcription in vitro. Due to the crucial role of E-cadherin in epithelia, tissue-specific effect of C-->A change on CDH1 transcription was tested and a case-control study was performed on patients affected with epithelial tumors.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0250-7005
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
26
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
4627-32
|
pubmed:dateRevised |
2008-11-21
|
pubmed:meshHeading |
pubmed-meshheading:17201188-Base Sequence,
pubmed-meshheading:17201188-Cadherins,
pubmed-meshheading:17201188-Case-Control Studies,
pubmed-meshheading:17201188-DNA Primers,
pubmed-meshheading:17201188-Genotype,
pubmed-meshheading:17201188-HeLa Cells,
pubmed-meshheading:17201188-Humans,
pubmed-meshheading:17201188-Polymorphism, Genetic,
pubmed-meshheading:17201188-Promoter Regions, Genetic,
pubmed-meshheading:17201188-Risk Factors
|
pubmed:articleTitle |
Functional analysis and case-control study of -160C/A polymorphism in the E-cadherin gene promoter: association with cancer risk.
|
pubmed:affiliation |
Department of Genetics and Microbiology, University of Pavia, 27100 Pavia, Italy.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|