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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2007-1-29
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pubmed:abstractText |
Toll-like receptors (TLRs) recognize distinct pathogen-associated molecular patterns and trigger anti-microbial host defense responses. Several in vitro and in vivo studies in mice indicate that TLR2 and TLR4 are involved in the defense against Streptococcus pneumoniae. Studies have revealed associations between polymorphisms in TLRs and human diseases. The effect of polymorphisms in TLR2 and TLR4 in the human defense to S. pneumoniae has not been studied.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1286-4579
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
15-20
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pubmed:meshHeading |
pubmed-meshheading:17196867-Adolescent,
pubmed-meshheading:17196867-Adult,
pubmed-meshheading:17196867-Aged,
pubmed-meshheading:17196867-Aged, 80 and over,
pubmed-meshheading:17196867-Child,
pubmed-meshheading:17196867-Child, Preschool,
pubmed-meshheading:17196867-Female,
pubmed-meshheading:17196867-Humans,
pubmed-meshheading:17196867-Infant,
pubmed-meshheading:17196867-Male,
pubmed-meshheading:17196867-Middle Aged,
pubmed-meshheading:17196867-Pneumonia, Pneumococcal,
pubmed-meshheading:17196867-Polymorphism, Genetic,
pubmed-meshheading:17196867-Streptococcus pneumoniae,
pubmed-meshheading:17196867-Toll-Like Receptor 2,
pubmed-meshheading:17196867-Toll-Like Receptor 4
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pubmed:year |
2007
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pubmed:articleTitle |
Toll-like receptor 2 and Toll-like receptor 4 polymorphisms in invasive pneumococcal disease.
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pubmed:affiliation |
Department of Laboratory Medicine, University Hospital Leuven, Centraal Dienstengebouw, Herestraat 49, B-3000 Leuven, Belgium.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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