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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2006-12-18
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pubmed:abstractText |
Rapid recurrence of severe hepatitis C (HCV) after liver transplantation is a major barrier to survival of the transplanted liver. While cyclosporine (CsA) in vitro has been shown to suppress HCV replication, an effect is not seen with tacrolimus (Tac). Evidence is inconsistent whether or how this translates to clinical practice. To expand the evidence on this issue, we analyzed graft survival and histological outcomes after liver transplantation for HCV hepatitis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0041-1345
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3625-8
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pubmed:meshHeading |
pubmed-meshheading:17175350-Biopsy,
pubmed-meshheading:17175350-Cyclosporine,
pubmed-meshheading:17175350-Databases, Factual,
pubmed-meshheading:17175350-Drug Therapy, Combination,
pubmed-meshheading:17175350-Female,
pubmed-meshheading:17175350-Graft Rejection,
pubmed-meshheading:17175350-Graft Survival,
pubmed-meshheading:17175350-Hepatitis C,
pubmed-meshheading:17175350-Humans,
pubmed-meshheading:17175350-Immunosuppressive Agents,
pubmed-meshheading:17175350-Liver Transplantation,
pubmed-meshheading:17175350-Longitudinal Studies,
pubmed-meshheading:17175350-Male,
pubmed-meshheading:17175350-Middle Aged,
pubmed-meshheading:17175350-Mycophenolic Acid,
pubmed-meshheading:17175350-Retrospective Studies,
pubmed-meshheading:17175350-Tacrolimus,
pubmed-meshheading:17175350-Transplantation, Homologous,
pubmed-meshheading:17175350-Treatment Outcome
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pubmed:year |
2006
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pubmed:articleTitle |
A cyclosporine-based immunosuppressive regimen may be better than tacrolimus for long-term liver allograft survival in recipients transplanted for hepatitis C.
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pubmed:affiliation |
Oregon Health Science University, USA. rayhills@ohsu.edu
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pubmed:publicationType |
Journal Article
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