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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2007-7-16
pubmed:abstractText
To assess cardiovascular magnetic resonance (CMR) findings in Takotsubo cardiomyopathy (TTC), 17 consecutive patients (15 women) with TTC who underwent left heart catheterization and gadolinium-enhanced CMR were evaluated. All patients had an abnormal electrocardiogram consisting of ST-segment elevation (n=8) and/or ST-segment depression (n=4) and/or T-wave inversion (n=14). One patient presented with left-bundle branch block. Left ventricular apical segments were involved in 10 patients (classical TTC), while they were not affected in 7 (variant form). Mean time delay between presentation and CMR was 9+/-7 days (range 3-24 days). CMR demonstrated complete resolution (n=4) or significant improvement of initial WMA in all cases. WMA were confined to basal and mid-ventricular segments (segments 1-12 in the 17-segment model) in the variant form, while they were virtually confined to the mid and apical left ventricle (segments 7-17) in classical TTC. Upon presentation ejection fraction by ventriculography was lower in classical TTC (36+/-7% vs. 58 +/-8%, p=0.0001). However, upon follow up ejection fraction by CMR was not different between classical and variant TTC (49+/-9% vs. 56+/-11%, p=0.23). Delayed hyperenhancement was absent in all but one patient. This finding may help differentiate TTC from entities with similar clinical presentations such as myocarditis and myocardial infarction, as the latter typically exhibits a subendocardial pattern of delayed hyperenhancement while the former usually displays a patchy subepicardial pattern.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1874-1754
pubmed:author
pubmed:issnType
Electronic
pubmed:day
21
pubmed:volume
120
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
205-11
pubmed:meshHeading
pubmed-meshheading:17175045-Adult, pubmed-meshheading:17175045-Aged, pubmed-meshheading:17175045-Aged, 80 and over, pubmed-meshheading:17175045-Cardiomyopathies, pubmed-meshheading:17175045-Contrast Media, pubmed-meshheading:17175045-Coronary Angiography, pubmed-meshheading:17175045-Diagnosis, Differential, pubmed-meshheading:17175045-Echocardiography, pubmed-meshheading:17175045-Electrocardiography, pubmed-meshheading:17175045-Female, pubmed-meshheading:17175045-Follow-Up Studies, pubmed-meshheading:17175045-Gadolinium DTPA, pubmed-meshheading:17175045-Heart Catheterization, pubmed-meshheading:17175045-Heart Ventricles, pubmed-meshheading:17175045-Humans, pubmed-meshheading:17175045-Injections, Intravenous, pubmed-meshheading:17175045-Magnetic Resonance Imaging, Cine, pubmed-meshheading:17175045-Male, pubmed-meshheading:17175045-Middle Aged, pubmed-meshheading:17175045-Retrospective Studies, pubmed-meshheading:17175045-Severity of Illness Index, pubmed-meshheading:17175045-Stroke Volume, pubmed-meshheading:17175045-Syndrome, pubmed-meshheading:17175045-Ventricular Dysfunction, Left
pubmed:year
2007
pubmed:articleTitle
Cardiovascular magnetic resonance findings in typical versus atypical forms of the acute apical ballooning syndrome (Takotsubo cardiomyopathy).
pubmed:affiliation
I. Medical Department, University Hospital Mannheim, Mannheim, Germany. dariush.haghi@med.ma.uni-heidelberg.de
pubmed:publicationType
Journal Article