| pubmed-article:17156122 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17156122 | lifeskim:mentions | umls-concept:C0008356 | lld:lifeskim |
| pubmed-article:17156122 | lifeskim:mentions | umls-concept:C0007603 | lld:lifeskim |
| pubmed-article:17156122 | lifeskim:mentions | umls-concept:C0014139 | lld:lifeskim |
| pubmed-article:17156122 | lifeskim:mentions | umls-concept:C0599896 | lld:lifeskim |
| pubmed-article:17156122 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:17156122 | pubmed:dateCreated | 2007-1-19 | lld:pubmed |
| pubmed-article:17156122 | pubmed:abstractText | Cholera toxin (CT), and members of the AB(5) family of toxins enter host cells and hijack the cell's endogenous pathways to induce toxicity. CT binds to a lipid receptor on the plasma membrane (PM), ganglioside GM1, which has the ability to associate with lipid rafts. The toxin can then enter the cell by various modes of receptor-mediated endocytosis and traffic in a retrograde manner from the PM to the Golgi and the endoplasmic reticulum (ER). Once in the ER, a portion of the toxin is unfolded and retro-translocated to the cytosol so as to induce disease. GM1 is the vehicle that carries CT from PM to ER. Thus, the toxin pathway from PM to ER is a lipid-based sorting pathway, which is potentially meditated by the determinants of the GM1 ganglioside structure itself. | lld:pubmed |
| pubmed-article:17156122 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17156122 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17156122 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17156122 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17156122 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17156122 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17156122 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:17156122 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17156122 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17156122 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:17156122 | pubmed:issn | 0378-1097 | lld:pubmed |
| pubmed-article:17156122 | pubmed:author | pubmed-author:LencerWayne... | lld:pubmed |
| pubmed-article:17156122 | pubmed:author | pubmed-author:ChinnapenDani... | lld:pubmed |
| pubmed-article:17156122 | pubmed:author | pubmed-author:SaslowskyDavi... | lld:pubmed |
| pubmed-article:17156122 | pubmed:author | pubmed-author:ChinnapenHima... | lld:pubmed |
| pubmed-article:17156122 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17156122 | pubmed:volume | 266 | lld:pubmed |
| pubmed-article:17156122 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17156122 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17156122 | pubmed:pagination | 129-37 | lld:pubmed |
| pubmed-article:17156122 | pubmed:dateRevised | 2011-10-11 | lld:pubmed |
| pubmed-article:17156122 | pubmed:meshHeading | pubmed-meshheading:17156122... | lld:pubmed |
| pubmed-article:17156122 | pubmed:meshHeading | pubmed-meshheading:17156122... | lld:pubmed |
| pubmed-article:17156122 | pubmed:meshHeading | pubmed-meshheading:17156122... | lld:pubmed |
| pubmed-article:17156122 | pubmed:meshHeading | pubmed-meshheading:17156122... | lld:pubmed |
| pubmed-article:17156122 | pubmed:meshHeading | pubmed-meshheading:17156122... | lld:pubmed |
| pubmed-article:17156122 | pubmed:meshHeading | pubmed-meshheading:17156122... | lld:pubmed |
| pubmed-article:17156122 | pubmed:meshHeading | pubmed-meshheading:17156122... | lld:pubmed |
| pubmed-article:17156122 | pubmed:meshHeading | pubmed-meshheading:17156122... | lld:pubmed |
| pubmed-article:17156122 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:17156122 | pubmed:articleTitle | Rafting with cholera toxin: endocytosis and trafficking from plasma membrane to ER. | lld:pubmed |
| pubmed-article:17156122 | pubmed:affiliation | GI Cell Biology, Children's Hospital, Boston, MA 21115, USA. | lld:pubmed |
| pubmed-article:17156122 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17156122 | pubmed:publicationType | Review | lld:pubmed |
| pubmed-article:17156122 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
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