17145805

Source:http://linkedlifedata.com/resource/pubmed/id/17145805

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0031715, umls-concept:C0033640, umls-concept:C0162638, umls-concept:C1172465, umls-concept:C1292733, umls-concept:C1513095
pubmed:issue	23
pubmed:dateCreated	2006-12-5
pubmed:abstractText	Arsenic is a valuable therapeutic tool in cancer treatment. Lymphokine-activated killer T-cell-originated protein kinase (TOPK) is highly expressed in cancer cells, but its specific function is still unknown. We investigated the role of TOPK in arsenic-induced apoptosis in RPMI7951 human melanoma cells.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/CA111356, http://linkedlifedata.com/resource/pubmed/grant/CA111536, http://linkedlifedata.com/resource/pubmed/grant/CA77646, http://linkedlifedata.com/resource/pubmed/grant/R01 CA077646-05, http://linkedlifedata.com/resource/pubmed/grant/R01 CA111356-01, http://linkedlifedata.com/resource/pubmed/grant/R01 CA111536-01A1
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9502500
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Arsenites, http://linkedlifedata.com/resource/pubmed/chemical/H2AFX protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Histones, http://linkedlifedata.com/resource/pubmed/chemical/PDZ-binding kinase, http://linkedlifedata.com/resource/pubmed/chemical/Protein-Serine-Threonine Kinases, http://linkedlifedata.com/resource/pubmed/chemical/RNA, Small Interfering, http://linkedlifedata.com/resource/pubmed/chemical/arsenite
pubmed:status	MEDLINE
pubmed:month	Dec
pubmed:issn	1078-0432
pubmed:author	pubmed-author:AbeYasuhitoY, pubmed-author:BodeAnn MAM, pubmed-author:DongZigangZ, pubmed-author:HigginsLeeAnnL, pubmed-author:LuChengrongC, pubmed-author:TatsumiYasuakiY, pubmed-author:ZhuFengF, pubmed-author:ZykovaTatyana ATA
pubmed:issnType	Print
pubmed:day	1
pubmed:volume	12
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	6884-93
pubmed:dateRevised	2010-12-3
pubmed:meshHeading	pubmed-meshheading:17145805-Humans, pubmed-meshheading:17145805-Animals, pubmed-meshheading:17145805-Mice, pubmed-meshheading:17145805-Arsenites, pubmed-meshheading:17145805-Phosphorylation, pubmed-meshheading:17145805-Histones, pubmed-meshheading:17145805-Melanoma, pubmed-meshheading:17145805-Chromatography, Liquid, pubmed-meshheading:17145805-Protein Binding, pubmed-meshheading:17145805-Dose-Response Relationship, Drug, pubmed-meshheading:17145805-Mass Spectrometry, pubmed-meshheading:17145805-Structure-Activity Relationship, pubmed-meshheading:17145805-Cell Line, Tumor

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