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rdf:type |
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lifeskim:mentions |
umls-concept:C0006826,
umls-concept:C0010592,
umls-concept:C0021079,
umls-concept:C0021080,
umls-concept:C0022646,
umls-concept:C0150369,
umls-concept:C0239998,
umls-concept:C0392762,
umls-concept:C0439849,
umls-concept:C0450127,
umls-concept:C1709518,
umls-concept:C1709854,
umls-concept:C2745955
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pubmed:issue |
10
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|
pubmed:dateCreated |
2006-11-28
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|
pubmed:abstractText |
At present it is unclear which dose and consecutive blood levels of cyclosporine A (CsA) are optimal with respect to immunosuppressive efficacy and drug specific side effects at the level of individual patients. Several pharmacodynamic measures of CsA effects have been proposed, but have not become clinical routine yet. Besides the lack of practicability, the biological relevance of these assays has not been determined so far.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0041-1337
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:day |
27
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pubmed:volume |
82
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1280-5
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:17130775-Adult,
pubmed-meshheading:17130775-Aged,
pubmed-meshheading:17130775-Analysis of Variance,
pubmed-meshheading:17130775-Cyclosporine,
pubmed-meshheading:17130775-Drug Monitoring,
pubmed-meshheading:17130775-Female,
pubmed-meshheading:17130775-Gene Expression Regulation,
pubmed-meshheading:17130775-Granulocyte-Macrophage Colony-Stimulating Factor,
pubmed-meshheading:17130775-Humans,
pubmed-meshheading:17130775-Immunosuppression,
pubmed-meshheading:17130775-Immunosuppressive Agents,
pubmed-meshheading:17130775-Infection,
pubmed-meshheading:17130775-Interferon-gamma,
pubmed-meshheading:17130775-Interleukin-2,
pubmed-meshheading:17130775-Kidney Transplantation,
pubmed-meshheading:17130775-Male,
pubmed-meshheading:17130775-Middle Aged,
pubmed-meshheading:17130775-NFATC Transcription Factors,
pubmed-meshheading:17130775-Neoplasms,
pubmed-meshheading:17130775-Postoperative Complications,
pubmed-meshheading:17130775-Recurrence
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pubmed:year |
2006
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pubmed:articleTitle |
Pharmacodynamic monitoring of cyclosporine a in renal allograft recipients shows a quantitative relationship between immunosuppression and the occurrence of recurrent infections and malignancies.
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pubmed:affiliation |
Department of Nephrology, University of Heidelberg, Heidelberg, Germany. claudia.sommerer@med.uni-heidelberg.de
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pubmed:publicationType |
Journal Article
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