rdf:type |
|
lifeskim:mentions |
umls-concept:C0001047,
umls-concept:C0017337,
umls-concept:C0033684,
umls-concept:C0043481,
umls-concept:C0086369,
umls-concept:C0231337,
umls-concept:C0302583,
umls-concept:C0332161,
umls-concept:C0456205,
umls-concept:C1123020,
umls-concept:C1550605,
umls-concept:C1998811
|
pubmed:issue |
5803
|
pubmed:dateCreated |
2006-11-24
|
pubmed:databankReference |
|
pubmed:abstractText |
Enhancing the nutritional value of food crops is a means of improving human nutrition and health. We report here the positional cloning of Gpc-B1, a wheat quantitative trait locus associated with increased grain protein, zinc, and iron content. The ancestral wild wheat allele encodes a NAC transcription factor (NAM-B1) that accelerates senescence and increases nutrient remobilization from leaves to developing grains, whereas modern wheat varieties carry a nonfunctional NAM-B1 allele. Reduction in RNA levels of the multiple NAM homologs by RNA interference delayed senescence by more than 3 weeks and reduced wheat grain protein, zinc, and iron content by more than 30%.
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pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
1095-9203
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:day |
24
|
pubmed:volume |
314
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1298-301
|
pubmed:dateRevised |
2007-3-19
|
pubmed:meshHeading |
pubmed-meshheading:17124321-Amino Acid Sequence,
pubmed-meshheading:17124321-Base Sequence,
pubmed-meshheading:17124321-Cloning, Molecular,
pubmed-meshheading:17124321-Frameshift Mutation,
pubmed-meshheading:17124321-Genes, Plant,
pubmed-meshheading:17124321-Iron,
pubmed-meshheading:17124321-Molecular Sequence Data,
pubmed-meshheading:17124321-Plant Leaves,
pubmed-meshheading:17124321-Plant Proteins,
pubmed-meshheading:17124321-Plants, Genetically Modified,
pubmed-meshheading:17124321-Protein Structure, Tertiary,
pubmed-meshheading:17124321-Quantitative Trait Loci,
pubmed-meshheading:17124321-RNA, Plant,
pubmed-meshheading:17124321-RNA Interference,
pubmed-meshheading:17124321-Transcription Factors,
pubmed-meshheading:17124321-Triticum,
pubmed-meshheading:17124321-Zinc
|
pubmed:year |
2006
|
pubmed:articleTitle |
A NAC Gene regulating senescence improves grain protein, zinc, and iron content in wheat.
|
pubmed:affiliation |
Department of Plant Sciences, University of California, One Shields Avenue, Davis, CA 95616, USA.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
|