Linked Life Data

17111403

Source:http://linkedlifedata.com/resource/pubmed/id/17111403

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2006-11-22
pubmed:abstractText
Pregnancy is associated with considerable physiological adaptations, some of which long outlast the state of pregnancy. Although it is well documented that pregnancy produces alterations of the hypothalamus-pituitary-adrenal axis, the longer-term effects of pregnancy on this system have not been systematically examined in humans. Subjects in the present study were 159 nulliparous and 265 parous women. Data analysis revealed no impact of parity on baseline activity (salivary cortisol: response to awakening, F </= .03, day profile: F </= 3.89, both n.s.). In a subsample, similar results were obtained for dexamethasone-suppressed salivary cortisol levels (all F </= 1.45 n.s., n = 45), as well as salivary cortisol, total cortisol, and ACTH responses to stimulation with a psychosocial stress protocol (all F </= .93 n.s., n = 47). These findings suggest that parity is not associated with long-term alterations of hypothalamus-pituitary-adrenal axis activity, and postpregnancy measures can, therefore, be used as proxy markers for a woman's prepregnancy status of this system.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0012-1630
pubmed:author
pubmed:copyrightInfo
(c) 2006 Wiley Periodicals, Inc.
pubmed:issnType
Print
pubmed:volume
48
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
703-11
pubmed:dateRevised
2007-12-3
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Parity does not alter baseline or stimulated activity of the hypothalamus-pituitary-adrenal axis in women.
pubmed:affiliation
Department of Psychology and Social Behavior, University of California, Irvine, 3340 Social Ecology II, Irvine, CA 92697-7085, USA. ifederen@uci.edu
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural