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rdf:type |
|
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lifeskim:mentions |
umls-concept:C0004083,
umls-concept:C0017337,
umls-concept:C0021965,
umls-concept:C0039485,
umls-concept:C0040135,
umls-concept:C0175630,
umls-concept:C0205098,
umls-concept:C0332307,
umls-concept:C0333641,
umls-concept:C0549193,
umls-concept:C1882417
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|
pubmed:issue |
2
|
|
pubmed:dateCreated |
2007-2-7
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|
pubmed:abstractText |
Thyroid function has been related to Alzheimer disease (AD) and neuroimaging markers thereof. Whether thyroid dysfunction contributes to or results from developing AD remains unclear. Variations in the deiodinase type 1 (DIO1) and type 2 (DIO2) genes that potentially alter thyroid hormone bioactivity may help in elucidating the role of thyroid function in AD.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
|
|
pubmed:issn |
0021-972X
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
92
|
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pubmed:owner |
NLM
|
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pubmed:authorsComplete |
Y
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pubmed:pagination |
636-40
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:17105838-Aged,
pubmed-meshheading:17105838-Aged, 80 and over,
pubmed-meshheading:17105838-Aging,
pubmed-meshheading:17105838-Alzheimer Disease,
pubmed-meshheading:17105838-Amygdala,
pubmed-meshheading:17105838-Atrophy,
pubmed-meshheading:17105838-Early Diagnosis,
pubmed-meshheading:17105838-Female,
pubmed-meshheading:17105838-Genetic Linkage,
pubmed-meshheading:17105838-Genetic Markers,
pubmed-meshheading:17105838-Hippocampus,
pubmed-meshheading:17105838-Humans,
pubmed-meshheading:17105838-Iodide Peroxidase,
pubmed-meshheading:17105838-Magnetic Resonance Imaging,
pubmed-meshheading:17105838-Male,
pubmed-meshheading:17105838-Middle Aged,
pubmed-meshheading:17105838-Polymorphism, Genetic,
pubmed-meshheading:17105838-Temporal Lobe,
pubmed-meshheading:17105838-Thyroid Diseases,
pubmed-meshheading:17105838-Thyroxine,
pubmed-meshheading:17105838-Triiodothyronine
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|
pubmed:year |
2007
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|
pubmed:articleTitle |
The association of polymorphisms in the type 1 and 2 deiodinase genes with circulating thyroid hormone parameters and atrophy of the medial temporal lobe.
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pubmed:affiliation |
Department of Epidemiology, Biostatistics, Erasmus Medical Center, 3000 DR Rotterdam, The Netherlands.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
