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rdf:type |
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|
lifeskim:mentions |
|
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pubmed:issue |
5
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pubmed:dateCreated |
2006-11-14
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|
pubmed:abstractText |
Chronic hepatitis C virus (HCV) infection is the leading indication for liver transplantation. Clinical evidence suggests that particular immunosuppressive agents can have an influence on HCV recurrence. Cyclosporine A (CsA) specifically inhibits HCV replication through blocking the viral RNA polymerase enzyme NS5B. In this study, we investigated the effect of mycophenolic acid (MPA) and other immunosuppressants on HCV replication.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
|
|
pubmed:issn |
0016-5085
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
131
|
|
pubmed:owner |
NLM
|
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1452-62
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pubmed:meshHeading |
pubmed-meshheading:17101321-Antiviral Agents,
pubmed-meshheading:17101321-Cell Line, Tumor,
pubmed-meshheading:17101321-Cell Proliferation,
pubmed-meshheading:17101321-Cyclosporine,
pubmed-meshheading:17101321-Drug Synergism,
pubmed-meshheading:17101321-Guanosine,
pubmed-meshheading:17101321-Hepacivirus,
pubmed-meshheading:17101321-Humans,
pubmed-meshheading:17101321-Immunosuppressive Agents,
pubmed-meshheading:17101321-Interferon-alpha,
pubmed-meshheading:17101321-Mycophenolic Acid,
pubmed-meshheading:17101321-Viral Nonstructural Proteins,
pubmed-meshheading:17101321-Virus Replication
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pubmed:year |
2006
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|
pubmed:articleTitle |
Mycophenolic acid inhibits hepatitis C virus replication and acts in synergy with cyclosporin A and interferon-alpha.
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pubmed:affiliation |
Department of Surgery, Erasmus MC-University Medical Center, Rotterdam, The Netherlands.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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