17095221

Source:http://linkedlifedata.com/resource/pubmed/id/17095221

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0003805, umls-concept:C0006142, umls-concept:C0011923, umls-concept:C0031268, umls-concept:C0032743, umls-concept:C0035647, umls-concept:C0220781, umls-concept:C0243071, umls-concept:C0450442, umls-concept:C1522485, umls-concept:C1708632, umls-concept:C1883254
pubmed:issue	2
pubmed:dateCreated	2007-1-15
pubmed:abstractText	Aromatase is a particularly good target in the treatment of estrogen receptor positive breast cancer. Novel carbon-11 labeled sulfonanilide analogues, N-[11C]methyl-N-(2-alkyloxy-4-nitrophenyl)-methanesulfonamides ([11C]3a-f, alkyl=propyl, isopropyl, 1-ethyl-propyl, cyclopentyl, cyclohexyl, and cyclohexylethyl), were designed and synthesized as potential PET agents for imaging of aromatase in breast cancer.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9107377
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Anilides, http://linkedlifedata.com/resource/pubmed/chemical/Aromatase Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Carbon Radioisotopes, http://linkedlifedata.com/resource/pubmed/chemical/Cyclooxygenase 2 Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Indicators and Reagents, http://linkedlifedata.com/resource/pubmed/chemical/N-(2-cyclohexyloxy-4-nitrophenyl)met..., http://linkedlifedata.com/resource/pubmed/chemical/Nitrobenzenes, http://linkedlifedata.com/resource/pubmed/chemical/Radiopharmaceuticals, http://linkedlifedata.com/resource/pubmed/chemical/Sulfonamides, http://linkedlifedata.com/resource/pubmed/chemical/Tetrazolium Salts, http://linkedlifedata.com/resource/pubmed/chemical/Thiazoles, http://linkedlifedata.com/resource/pubmed/chemical/thiazolyl blue
pubmed:status	MEDLINE
pubmed:month	Jan
pubmed:issn	0960-894X
pubmed:author	pubmed-author:GaoMingzhangM, pubmed-author:LacyGabrielleG, pubmed-author:MillerKathy DKD, pubmed-author:SledgeGeorge WGW, pubmed-author:WebbS LSL, pubmed-author:ZhengQi-HuangQH
pubmed:issnType	Print
pubmed:day	15
pubmed:volume	17
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	332-6
pubmed:meshHeading	pubmed-meshheading:17095221-Adult, pubmed-meshheading:17095221-Anilides, pubmed-meshheading:17095221-Aromatase Inhibitors, pubmed-meshheading:17095221-Breast Neoplasms, pubmed-meshheading:17095221-Carbon Radioisotopes, pubmed-meshheading:17095221-Cell Line, Tumor, pubmed-meshheading:17095221-Cyclooxygenase 2 Inhibitors, pubmed-meshheading:17095221-Drug Design, pubmed-meshheading:17095221-Female, pubmed-meshheading:17095221-Humans, pubmed-meshheading:17095221-Indicators and Reagents, pubmed-meshheading:17095221-Isotope Labeling, pubmed-meshheading:17095221-Nitrobenzenes, pubmed-meshheading:17095221-Positron-Emission Tomography, pubmed-meshheading:17095221-Radiopharmaceuticals, pubmed-meshheading:17095221-Sulfonamides, pubmed-meshheading:17095221-Tetrazolium Salts, pubmed-meshheading:17095221-Thiazoles
pubmed:year	2007
pubmed:articleTitle	Synthesis of carbon-11 labeled sulfonanilide analogues as new potential PET agents for imaging of aromatase in breast cancer.
pubmed:affiliation	Department of Radiology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't