Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2006-11-22
pubmed:abstractText
We report on an autopsy case of a 44-year-old woman who died of combined hepatic and renal failure and bacterial infection. Postmortem examination revealed advanced liver cirrhosis and membranoproliferative glomerulonephritis (MPGN), caused by clinically inapparent hepatitis C virus (HCV) infection. The diagnosis was confirmed by reverse transcription polymerase chain reaction (RT-PCR) of HCV RNA in formalin-fixed, paraffin-embedded (FFPE) liver tissue. We conclude that liver cirrhosis and concomitant MPGN should arouse suspicion of HCV infection despite ambiguous or negative results from serological analyses. Specimens of FFPE liver tissue may be used for the diagnosis of HCV infection, even if the tissue was obtained in a postmortem examination.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0344-0338
pubmed:author
pubmed:issnType
Print
pubmed:volume
202
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
891-4
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Liver cirrhosis and membranoproliferative glomerulonephritis caused by inapparent hepatitis C virus infection.
pubmed:affiliation
Department of Pathology, Otto-von-Guericke-University, Magdeburg, Germany. kalinski@medizin.uni-magdeburg.de
pubmed:publicationType
Journal Article, Case Reports